Molecular Research Assistant - Computational Genomics

Job No: GC201927
Location: Darlinghurst, NSW

The research program of the Single Cell and Computational Genomics laboratory focuses on demonstrating the genomic mechanisms by which loci contribute to complex human diseases, and working towards early stage diagnosis methods and targeted therapeutics. To do so, we apply existing computational approaches, and develop our own statistical genetics methods for analysis of large-scale next generation sequencing data. Following in silico experiments, we perform functional validation of statistical observations using molecular techniques such as high-throughput genome editing and cell phenotyping. We have a very significant focus on the use of single cell sequence data and technology, due to the phenomenal resolution it offers in being able to identify differences in the genomics processes between individual cells. The laboratory drives projects in a number of areas of medical genomics research, but we also believe strongly in the value of collaboration between groups with differing expertise. We are committed to reproducible research practices, and open data policies.

We are currently seeking a talented, experienced Research Assistant to contribute to the busy translational research in the Computational Genomics lab focused on using single cell genomics to guide functional biological experiments. The role will involve managing patient recruitment, biobanking, cell preparation and in vitro assays as well as planning and executing functional experiments are core to the role. 

The Opportunity

Reporting to the Lab Head, Associate Professor Joseph Powell, the key responsibilities include the following: 

  • Assist with patient recruitment to biobanking studies on the St Vincent’s Hospital Campus
  • Management of biobanking work flow, procedures and data storage
  • Planning and executing functional in vitro assays including flow cytometry and cellular genomics
  • Participate in research that supports grant funding (i.e. participate in generating preliminary proof of principle results for complex high-end projects)
  • Administration of the experimental analysis, patient collections and biobanking
  • Establish and maintain excellent records of experimental work  

The position will be offered part-time (4 days per week) for 2 years in the first instance.

About You

You will have the following key skills and experiences:

  • Bachelor’s degree in a relevant area of science
  • Experience in cell culture, biobanking, flow cytometry, immunohistochemistry and single cell sequencing
  • Experience in translational research programs containing patient samples
  • Experience validating genomics results in functional in vitro assays
  • Excellent interpersonal skills
  • Broad knowledge of research/healthcare systems
  • The ability to assess priorities and manage competing deadlines
  • Excellent written and oral communication, presentation and interpersonal skills to interact with internal and external stakeholders

How to Apply

All applications must be submitted via the Garvan Careers site via the link below. Applications from other sites/channels will unfortunately not be considered.

https://garvan.applynow.net.au/jobs/GC201927

Your application should include: 

  • A cover letter
  • Your resume including at least 2 referees
  • Copies of relevant qualifications / academic transcripts

Only applicants with full working rights in Australia are eligible to apply for this role.

Closing Date

The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.

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